Bubble Boy (2001)

Jimmy is young man who was born without an immune system and has lived his life within a plastic bubble in his bedroom… who pines for the sweet caresses of girl-next-door Chloe. But when Chloe decides to marry her high school boyfriend, Jimmy — bubble suit and all — treks cross-country to stop her. Swoosie Kurtz, as Jimmy’s overprotective mom, co-stars along with Fabio, who portrays the leader of a religious cult.